Jan Claassen, MD, FNCS

Academic Appointments

  • Associate Professor of Neurology at CUMC

Current Administrative Positions

  • Head of Neurocritical Care and Medical Director of the Neurological Intensive Care Unit
Jan Claassen, MD, FNCS

Dr. Claassen is an Associate Professor of Neurology and the Director of Critical Care Neurology at Columbia University. He is an Associate Attending Physician at NewYork-Presbyterian/Columbia University Medical Center and the Medical Director of the Neurocritical Care Unit. Dr. Claassen received his medical degree from the University of Hamburg, Germany, and completed residency training in Neurology, and Fellowship training in Neurocritical Care and Epilepsy at Columbia University. He is board certified in Neurology and Neurocritical Care.

Dr Claassen is a nationally and internationally recognized expert in the treatment of neurological intensive care. He is an expert in coma, status epilepticus and brain hemorrhages. He served on the board of directors and as the co-chair for guidelines development for the Neurocritical Care Society. He has championed the use of innovative brain monitoring techniques including continuous EEG monitoring. His sits on the editorial board of Annals of Neurology and Neurocritical Care.

Dr Claassen’s research characterizes physiologic changes following acute brain injury, focusing on novel treatment approaches to potentially improve patient outcomes. He is a widely recognized expert on disorders of consciousness. He has published more than 300 journal articles, book chapters, and reviews. He is the co-editor of the seminal monograph Plum and Posner’s: Diagnosis and Treatment of Stupor and Coma. His research is supported by federal R01 and foundation grants

He has published more than 150 journal articles, book chapters, and reviews. His research characterizes physiologic changes following acute brain injury, focusing on novel treatment approaches to potentially improve patient outcomes.

Departmental Appointments

  • Department of Neurology
    Division of Critical Care and Hospitalist Neurology

Languages Spoken

(in addition to English)

  • German

Education and Training

  • University of Hamburg, Germany
  • Residency: Harlem Hospital Center
  • Residency: NewYork-Presbyterian Hospital/Columbia University Medical Center
  • Fellowship: NewYork-Presbyterian Hospital/Columbia University Medical Center

Lab Locations

  • CUMC/Neurological Institute of New York

    710 West 168th Street
    New York, NY 10032
    Phone:
    (212) 305-7236

NIH Grants

  • APROSPECTIVE, MULTI-CENTER, DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED, PARALLEL-GROUP, PHASE 3 STUDY TO ASSESS THE EFFICACY AND SAFETY OF CLAZOSENTAN IN PREVENTING CLINICAL DETERIORATION DUE TO DELAYED CEREBRAL ISCHEMIA (DCI), IN ADULT SUBJECTS (P&S Industry Clinical Trial)

    Feb 7 2020 - Feb 7 2025

    DEEP PROBABILISTIC PREDICTIVE MODELS FOR STROKE AND CORONARY HEART DISEASE (Federal Gov)

    Sep 1 2019 - Jun 30 2024

    RECONFIG - RECOVERY OF CONCIOUSNESS FOLLOWING INTRACEREBRAL HEMORRHAGE (Federal Gov)

    Jun 15 2019 - Mar 31 2024

    PROSPECTIVE,RANDOMIZED, INTERVENTIONAL TRIAL IN ADULT SUBJECTS WITH OUT-OF-HOSPITAL CARDIAC ARREST COMPARING TREATMENT WITH STANDARD-OF-CARE POST?CARDIAC ARREST INTENSIVE CARE WHICH IS TARGETED TEMPERATURE MANAGEMENT [TTM]) TO STANDARD-OF-CARE (P&S Industry Clinical Trial)

    Nov 12 2018 - Nov 12 2023

    IMPACT OF FEVER PREVENTION IN BRAIN INJURED PATIENTS (P&S Industry Clinical Trial)

    May 23 2018 - May 23 2023

    THE EPILEPSY BIOINFORMATICS STUDY FOR ANTIEPILEPTOGEIC THERAPY (EPIBIOS4RX) (Federal Gov)

    Jan 15 2017 - Nov 30 2021

    BASIC - BRAIN-COMPUTER-INTERFACE PRACTICAL APPLICATION IN THE INTENSIVE CARE UNIT: A PILOT STUDY (Federal Gov)

    Jul 1 2019 - Jun 30 2021

    MECHANISTIC MACHINE LEARNING (Federal Gov)

    Sep 20 2017 - Aug 31 2020

    SETPOINT II TRIAL: STROKE-RELATED EARLY TRACHEOSTOMY VS PROLONGED OROTRACHEAL INTUBATION IN NEUROCRITICAL CARE TRIAL II (Private)

    Jan 1 2018 - Dec 31 2019

    MECHANISTIC MACHINE LEARNING (Federal Gov)

    Sep 1 2018 - Aug 31 2019

    MULTI-ARM OPTIMIZATION OF STROKE THROMBOLYSIS (MOST) STROKE TRIAL (Federal Gov)

    Jun 1 2018 - Apr 30 2019

    ANOPEN-LABEL STUDY TO EVALUATE THE SAFETY, EFFICACY, AND PHARMACOKINETICS OF SAGE-547 INJECTION AS ADJUNCTIVE THERAPY IN THE TREATMENT OF ADULTS WITH SUPER-REFRACTORY STATUS EPILEPTICUS (P&S Industry Clinical Trial)

    Jan 14 2014 - Jan 14 2019

    UTILITY OF INTRAVENOUS LACOSAMIDE COMPARED WITH FOSPHENYTOIN IN THE TREATMENT OF PATIENTS WITH FREQUENT NONCONVULSIVE SEIZURES (P&S Industry Clinical Trial)

    Oct 30 2013 - Oct 30 2018

    COMBINING CLINICAL DATA AD TRANSDERMAL ANALYSIS OF WHOLE BLOOD TO CREATE A NEXT-GENERATION WEARABLE DEVICE (Federal Gov)

    Aug 1 2016 - Sep 14 2017

    COMBINING CLINICAL DATA AD TRANSDERMAL ANALYSIS OF WHOLE BLOOD TO CREATE A NEXT-GENERATION WEARABLE DEVICE (Federal Gov)

    Sep 15 2016 - Sep 14 2017

    A COLLABORATIVE STUDY OF RECOVERY OF CONSCIOUSNESS AFTER SEVERE BRAIN INJURY - PHASE II (Private)

    Aug 1 2013 - Jul 31 2017

    FUTILITY STUDY OF DEFEROXAMINE MESYLATE IN INTRACEREBRAL HEMORRHAGE (I-DEF) (Federal Gov)

    Sep 1 2014 - Aug 31 2016

    SAFETY EVALUATION OF 3K3AAPC IN ISCHEMIC STROKE-RHAPSODY-NEURONEXT (Federal Gov)

    Jul 1 2015 - Jun 30 2016

    NEUROLOGICAL EMERGENCIES TREATMENT TRIALS (NETT)- PROTECT (Federal Gov)

    Sep 1 2013 - Jun 30 2016

    CASUAL INFERENCE IN LARGE - SCALE TIME - SERIES WITH RARE EVENTS AND LATENT VARIABLES (Federal Gov)

    Jun 1 2013 - May 31 2016

    NEUROLOGICAL EMERGENCIES TREATMENT TRIALS (NETT)- ESETT (Federal Gov)

    Sep 30 2014 - Feb 29 2016

    NEUROLOGICAL EMERGENCIES TREATMENT TRIALS (NETT) (Federal Gov)

    Sep 1 2013 - Jan 31 2016

    NEUROLOGICAL EMERGENCIES TREATMENT TRIALS (NETT)-RAMPART (Federal Gov)

    Sep 1 2013 - May 31 2015

    CRITICAL CARE EEG MONITORING RESEARCH CONSORTIUM (Private)

    Jan 1 2014 - Dec 31 2014

    NEUROLOGICAL EMERGENCIES TREATMENT TRIALS (NETT)-SHINE (Federal Gov)

    Sep 1 2013 - Jul 31 2014

    SEIZURE DETECTION IN CRITICALLY ILL PATIENTS (Private)

    Jun 5 2012 - Jun 4 2013

Publications

Please visit Dr. Claassen's Google Scholars page.

For a complete list of publications, please visit PubMed.gov