Familial Test Helps Detect Genes that Cause Complex Diseases

Baylor College of Medicine
By Allison Huseman
Featuring Dr. Richard Mayeux

A team of researchers at Baylor College of Medicine has developed a family-based association test that improves the detection in families of rare disease-causing variants of genes involved in complex conditions such as Alzheimer’s. The method is called the rare-variant generalized disequilibrium test (RV-GDT), and it incorporates rare, as opposed to common, genetic variants into the analysis. [read more]